More Advanced Prostate Cancers After USPSTF Guideline Change -- Diagnoses increased by 3% per year in 2014 to 2021

following recommendation against PSA screening

"After years of declining rates, prostate cancer diagnoses increased by 3% per year from 2014 to 2021, with the steepest rise seen in advanced disease, according to a report from the American Cancer Society (ACS).

While new diagnoses of prostate cancer fell by 6.4% per year from 2007 to 2014, diagnoses increased by 2.4% annually for localized-stage disease, 4.6% annually for regional-stage disease, and 4.8% annually for distant-stage disease between 2017 and 2021, with trends varying by age group, reported Tyler B. Kratzer, MPH, and ACS colleagues in CA: A Cancer Journal for Cliniciansopens in a new tab or window.

At the same time, the decline in rates of prostate cancer mortality slowed from 3% to 4% per year during the 1990s and 2000s to 0.6% per year over the past decade, with substantially higher mortality rates among Black men versus white men.

"Our research highlighting the continued increases in prostate cancer incidence and persistent racial disparities underscores the need for redoubled efforts to understand the etiology of prostate cancer and optimize early detection," said Kratzer in a press releaseopens in a new tab or window.

Co-author Ahmedin Jemal, DVM, PhD, told MedPage Today that there could be a link between the U.S. Preventive Services Task Force (USPSTF) recommendationsopens in a new tab or window against prostate-specific antigen (PSA)-based screening for prostate cancer in 2008 and 2012opens in a new tab or window, and the observed increase in advanced prostate cancer diagnoses."


https://www.medpagetoday.com/hematologyoncology/prostatecancer/117297?mh=9701e5e556ac1543dfb2ab968550813c&xid=nl_mpt_Oncology_update_2025-09-05&zdee=gAAAAABm4uxvn5SAgpa5xYOjEigEAQDQRkAhu4TBX5CA0Y-Ne5nq63wV8FW92mTfJJfq-J92Zza9t0cgSw4IwOLHwJZFloDqiQyZOWJPNCMtMesditQWGBo%3D

One has to wonder if it was because of the USPSTF recommendation that President Biden was diagnosed late based on this recommendation:

"The USPSTF has since issued revised recommendations opens in a new tab or window saying that screening should be an individual decision for men between the ages of 55 and 69 in consultation with their physicians, and should be avoided in men ages 70 and over."