General Discussion
Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsYou know, this is a distinct possibility given the evidence:
Severe, Intolerable Fatigue Associated with Hyperresponse to Clopidogrel
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David I. Bass Christopher C. Young Min S. Park Michael J. Cruz Kate T. Carroll Kevin N. Vanent Chungeun Lee Rajeev D. Sen Dominick J. Angiolillo 5, Marco Cattaneo 6, Louis J. Kim 1 7 8, Michael R. Levitt
https://doi.org/10.1016/j.wneu.2021.09.075
Objective
Clopidogrel is a commonly used antiplatelet agent for the prevention of thromboembolic complications following neuroendovascular procedures, but anecdotal data have raised concern for the possibility that clopidogrel may induce severe, intolerable fatigue. The purpose of this study is to systematically investigate this phenomenon.
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Conclusions
A syndrome of severe fatigue and other constitutional symptoms is a rare but clinically significant side effect of hyperresponse to clopidogrel in patients undergoing neuroendovasular intervention.
Kud bee
or similar meds prescribed for similar purposes. Several different types of hypertensive drugs, cause exhaustion, including beta blockers.
CaliforniaPeggy
(155,704 posts)Could be.
IcyPeas
(24,604 posts)dweller
(27,572 posts)To comatose ?
Room temperature?
🤔
✌🏻
bucolic_frolic
(53,228 posts)Lots of treatments cause fatigue. That "washed-out" feeling: IV chelation. Droopy confusion: Anti-psychotics.
cachukis
(3,563 posts)in the game.
tinrobot
(11,870 posts)I'm surprised they found a brain.
Seriously, if he had brain surgery, that needs to be disclosed.
Wounded Bear
(63,486 posts)Haven't had that symptom so far and it's been several months.
PCIntern
(27,791 posts)It could be in combination with other medication hes taking including beta blockers and who knows what else?
Wounded Bear
(63,486 posts)Prairie_Seagull
(4,552 posts)I have contacted all of my docs about this and the response I get is, the fatigue is probably associated with something else. Like type 2 diabetes.
Without it however I am prone to significant TIA's. To the point where I really no longer go to the hospital. What would be another medication option?
I will be pointing to this study with a doc in near future.
Gore1FL
(22,737 posts)I'm always tired, but assume it has to do with my poor sleep habits and outcomes.
babylonsister
(172,479 posts)obviously. I hope he finds peace soon!
buzzycrumbhunger
(1,470 posts)I suppose clopidogrel could be a factor, though in my time as a pharmacy tech, we dispense tons of this and Ive never seen a patient with that complaint. I think its likely multifactorial, beginning with the fact hes OLD, has fecal and urinary incompetence, the frontotemporal dementia, probable escalating tertiary syphilis, and has been popping Adderall and other crap as he pleases, eats McDonalds garbage in huge quantities, yada, yada, yada.
I think its not unlikely that a new medication regime could indeed be one thing too many on top of all his other problems. If so, I vote that they double the dose and hurry him over the precipice.
PCIntern
(27,791 posts)And furthermore, who knows what else hes on at this could be interacting with? Anything is possible, considering that he has possibly not had the best advice or necessarily heeds any competent physicians advice.
sakabatou
(45,518 posts)While his napping could be chalked up to his health, we shouldn't come to a hasty conclusion.
PCIntern
(27,791 posts)I can do anything I please. I can come to any conclusion I want given they feed us no information and theres obviously a big problem. I can think he had a stroke, I can think he is on too many medications for his own good, I can think that theyre being implanted in his food by the CIA.
Aint no hasty conclusions here. Ive been watching this sociopath for 40 years. Anything I say is valid as anything anybody else says and try to prove me wrong.
llmart
(17,067 posts)He shows no "constitutional symptoms". He shits on our constitution every day.
Swede
(37,890 posts)canetoad
(19,821 posts)He has been told to stay off the Adderall (for health reasons).
buzzycrumbhunger
(1,470 posts)... that it might not be possible to blame one thing.
But hey, he's obviously getting worse so we all might have a happy Thanksgiving. Keep a good thought! 😉

CTyankee
(67,537 posts)What does this swelling indicate?
Hugin
(37,115 posts)Chemical toilet in the summer noon-day sun.