https://www.yahoo.com/news/articles/fda-strip-misleading-safety-warning-224507519.html

The FDA Will Strip the Misleading Safety Warning From Hormone Therapy. Here’s What This Means for You

Erica Sloan
Mon, November 10, 2025 at 2:45 PM PST

Much to the delight of ob-gyns long espousing the upsides of hormone therapy (a.k.a. hormone replacement therapy, or HRT) for menopause symptoms, the FDA announced today that HRT products will no longer have a “black box” warning. Originally added in 2003, the label calls out risks of conditions like breast cancer, heart attack, stroke, and dementia based on a large study called the Women’s Health Initiative (WHI)—it was stopped short in 2002 when researchers first spotted such potential for poor outcomes. But in the decades since, it’s been well-established that the data didn’t support the warning that followed.

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HHS.gov
https://www.hhs.gov › press-room › fact-sheet-fda-initiates-removal-of-black-box-warnings-from-menopausal-hormone-replacement-therapy-products.html

FACT SHEET: FDA Initiates Removal of "Black Box" Warnings from ...

TodayMenopausal hormone therapies, also commonly referred to as hormone replacement therapy or (HRT), are approved to provide relief from

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Every once in awhile, there's bound to be some good done even by total assholes. That, or there's still some decent holdovers still in the FDA

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Thanks for this.

and particularly QUALITY-of-.life-saving, health-saving medications and treatments for an entire generation.

The WHI (Women’s Health Initiative) study erroneously drew the conclusion that women who sought to treat menopause, save their sex lives, their bones, their joints, their hearts and their brains from the ravages of estrogen starvation were surely giving themselves cancer. Consequently, hormone replacement therapy all but dissapeared as an option for women in this phase of life. We were told to suck it up and suffer. Lie back, look at the ceiling and use more lube. Take antidepressants. Take a spin class. Take osteoporosis drugs that actually cause osteonecrosis of the jaw and femoral fractures.

Now they will be removing the black box warning that caused us to raise a generation of doctors that made women feel like shit for wanting to use this medication. Huge numbers refused to prescribe it at all Most of them would only “allow” you to use the tiniest doses possible, for the shortest amount of time possible and would constantly badger you to stop using it. Women are now terrified of it.

It was insane, and i hope this is the beginning of the end of it. The WHI did real harm to millions upon millions of women. It’s long past time for it to be disgraced

I’M FAWKING 75 YEARS OLD AND STILL GETTING THEM!!!!! I NEED DRUGS……PLEASE.

If you like I can PM you and get you set in the right direction

and so many of mine (I’m an older X at about 59.)

I was getting a prescription for years and I found the same Bi-estrogen cream formula I was getting from a compounding pharmacy on Amazon. You can read all the Amazon reviews on how so many women were helped.

If you take Bi-estrogen and you have a uterus you need progesterone too. Amazon carries both. Get the natural ones made from yams.

And so will not benefit bone, heart, brain health as pharmescutical HRT is proven to do. Some OTC estriol creams are quite lovely for the skin though.

Now all top NY hospitals have menopause depts and treat women with hormones. I heard women gynecologists from Langone Med Center on radio talking about how hormones can protect your heart especially if you go on as soon as you are menopausal.

Bio- identical hormones are popular - made from steroids from Mexican yams. I’ve been on bio-identicals for over 25 yrs as have some of my friends.

In the past, many hormones were made from horse urine - now newer forms like skin creams and patches made from yams and soy.

Yam and soy steroids had to be subjected to ingenious chemical modifications to have the same molecular structure as the natural hormones; for commercial success, they needed to be available in quantity, and isolated fairly efficiently, both of which required considerable ingenuity, as well as considerable patience with trial-and-error results.

Chemically, there is no distinction between these particular synthetic hormones and those from natural sources (not true of all steroids in use, by any means).

For the synthesis from steroids found in yams, read up on Russel Marker: https://www.acs.org/education/whatischemistry/landmarks/progesteronesynthesis.html

For soy steroids, see the work of Percy Julian: https://en.wikipedia.org/wiki/Percy_Lavon_Julian

PBS has shown docs on both men and their work. They were working on similar projects at about the same time, but that often happens in science, as new discoveries lead to whole new fields of study, which lead to new discoveries. "Success" wasn't a one-time thing either, so "who was first" is kind of a fuzzy question -- or at least a question with a fuzzy answer.

Its methodology and findings were flawed. For some time, women's advocates in the medical community have argued that women should have the option of HRT because of its benefits to mood, body changes, bone density, weight gain, hot flashes, etc... Doctors, particularly male doctors, have denied women that option. Women have had to fight to get HRT, and only certain specialist OBGYNs will prescribe it. RFK junior is an idiot, but he happens to be right on this ONE issue.

Actually, it's not just male doctors who refuse women HRT. The medical establishment in general knows nothing about menopause, so that when you go to a doctor with a complaint, they never tell you that it's a perimenopausal symptom because they don't even know. That happened with me. I had persistent migraines when I was perimenopausal, but they went away when I entered menopause. It would have been nice to know that at the time.

Here is a link to one, more recent NIH study on HRT: https://pmc.ncbi.nlm.nih.gov/articles/PMC11826161/

THAT WAS LIKE, 20 years ago……I’M STILL GETTING THOSE GAWD DAMN FLASHES and I SWEAR TO GAWD, I WON’T BE GETTING PREGNANT ANY TIME SOON!!!!

Is not having to get up at night to pee. I have a friend who was getting up 5 times a night to pee and that all stopped when she went on the hormones. Many people with chronic UTI’s say it helps.

For me - I initially went on them over 25 yrs ago for a better sex life- then noticed my mind seemed way sharper on them. I’ve never had a hot flash in my life -even before going on them. But I have thicker hair and less wrinkles than friends my age and believe it’s probably the estrogen - sometimes I’ll dab the cream on my face too!

I had a chiropractor initially give me my first prescription. I never had any problems with my various drs over the yrs prescribing the cream till I got a stubborn PA. That’s when my daughter told me I could get it on Amazon and for me it works just as well - as it was the same two estrogens in the same amts as my prescription- plus I got progesterone. In my initial prescription, the doc put a very tiny amt of testosterone but that’s by prescription only unless you use something like the herb ashwaganda.

Got an appointment NOV 21st, and you can be damn sure I’m getting that HRT pill back!!!!!