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Omaha Steve

(107,165 posts)
Mon Sep 29, 2025, 01:39 PM 21 hrs ago

A drug made from marijuana reduced back pain in a large study

Source: AP

By MATTHEW PERRONE
Updated 12:21 PM CDT, September 29, 2025

WASHINGTON (AP) — An experimental medication made from marijuana successfully reduced back pain in a new study, offering further support for the drug’s potential in treating one of the most common forms of chronic pain.

The 800-patient study by a German drugmaker is the latest evidence of the therapeutic properties of cannabis, which remains illegal under U.S. federal law even as most states have made it available for medical or recreational use.

Health officials in Canada and Europe have previously approved a pharmaceutical-grade form of cannabis for several types of pain, including nerve pain due to multiple sclerosis. In the U.S., the Food and Drug Administration has approved a drug containing CBD — one of the many non-intoxicating chemicals found in cannabis — to treat rare seizures in children with epilepsy.

Unlike that drug, known as Epidiolex, the new cannabis formula from drugmaker Vertanical contains THC, the active ingredient in marijuana that gets users high. But levels of the chemical are very low, essentially a microdose compared to what’s available in gummies, chocolate bars and other products sold at marijuana dispensaries in the U.S. The company said patients in the trial didn’t show any signs of drug abuse, dependence or withdrawal.



Read more: https://apnews.com/article/marijuana-cannabis-back-pain-study-vertanical-387d41a301dc9540b1f2823d28f2fc43

21 replies = new reply since forum marked as read
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A drug made from marijuana reduced back pain in a large study (Original Post) Omaha Steve 21 hrs ago OP
...and we'll never hear about it again. C Moon 19 hrs ago #1
Oh, on the contrary... OldBaldy1701E 17 hrs ago #8
thanks for posting this! glad to know about it nt orleans 19 hrs ago #2
In Science We Should Trust, eh men, and women. twodogsbarking 18 hrs ago #3
That makes more sense.. Tranquil72 18 hrs ago #4
The last THC pill approved was useless for nausea or pain. Usually my patients did better if they smoked or vaped. travelingthrulife 41 sec ago #21
Due to arthritis in whole spine, along with almost ever joint in my body, and spinal stenosis in neck, PAIN is constant Attilatheblond 18 hrs ago #5
My arthritis has progressed to encompass the whole spine, as well... slightlv 17 hrs ago #6
In AZ, a lot of Cannabis products are legal at licensed dispensaries. There is a steep tax on the stuff Attilatheblond 16 hrs ago #9
My sis and I have taken trips to DT KC in the past, slightlv 11 hrs ago #13
My husband has arthritis in the spine Tree Lady 16 hrs ago #11
Pain specialist tested the Medial Branch Block on me Attilatheblond 11 hrs ago #14
Gee, who would have thought. twodogsbarking 17 hrs ago #7
Yep. I often wonder if the Puritans put us on the wrong course about a lot of things. Attilatheblond 11 hrs ago #15
Good luck to hopefully soon better relief! electric_blue68 16 hrs ago #10
bookmarked -- for op and the replies nt orleans 12 hrs ago #12
Message auto-removed Name removed 3 hrs ago #16
Are you going to tell us vaxes are scams next? I've read that on right-wing sites. Bernardo de La Paz 2 hrs ago #17
Message auto-removed Name removed 2 hrs ago #19
I see you do your own research! Bernardo de La Paz 2 hrs ago #20
After two back surgeries, it's helped me. Emile 2 hrs ago #18

OldBaldy1701E

(9,153 posts)
8. Oh, on the contrary...
Mon Sep 29, 2025, 05:32 PM
17 hrs ago

They will love anything that will keep us working. They will try to figure out a way to downplay the fact that it is made from cannabis, but they love medical advances that keep us in the trenches.

My question is, as always, is the motivation for making this the ability to help control pain, or what I was saying, in that they just want to make sure we will work ourselves to death before we realize it?

(This is a somewhat rhetorical question...)

Tranquil72

(14 posts)
4. That makes more sense..
Mon Sep 29, 2025, 03:58 PM
18 hrs ago

From a medical perspective — isolating THC and CBD for specific uses rather than relying on the plant itself. I’m told that’s already working well in the context of chemotherapy, to relieve the nausea associated with the treatment.

travelingthrulife

(3,365 posts)
21. The last THC pill approved was useless for nausea or pain. Usually my patients did better if they smoked or vaped.
Tue Sep 30, 2025, 10:41 AM
41 sec ago

Attilatheblond

(7,342 posts)
5. Due to arthritis in whole spine, along with almost ever joint in my body, and spinal stenosis in neck, PAIN is constant
Mon Sep 29, 2025, 04:31 PM
18 hrs ago

Sound sleep for more than an hour or two at a time is impossible. I am up 2-4 times doing PT exercises just to be able to lie back down. Can't tolerate the normal pain pills doctors reluctantly give.

Tried CBD oil and it isn't much help.Finally tried cannabis gummies. Not a big fan of THC but it did allow some sleep. Further experiments with formulas and levels brought progress and the occasional decent night's sleep. But only used when pain and exhaustion made me wish for death.

Tried different gummies with different formulas. Finally found a gummy that really helps without a list of side affects. The dosage is as follows:

each gummy:
10MG of CBG (a cannabis component I had not read about until I tried these & did some research)
10MG of CBD
1MG of THC
and...............50MG of Theanine

Researching the CBG component showed me it is a good pain reliever, with the usual pain management dosage being 60MG for bad pain. Being sensitive to other medicine, I started slow, only one gummy, and gradually increased dosage every few days, noting how I felt and any side effects. Found that only 3 of these lil gems really helps pretty bad pain (my pain tolerance is WAY above normal as I've had so much for so long, it takes me barely able to walk or sleep for a few days before I try any medicine)

Sleep is now possible, and I take at least one of these fairly regularly. Unlike the higher THC items, these do not make my mouth/throat so dry that I have to sip water all night, which definitely interferes with sleep.

Life is tolerable, again, even pleasant some days and I can get some household/yard chores done if I pace myself.



slightlv

(6,625 posts)
6. My arthritis has progressed to encompass the whole spine, as well...
Mon Sep 29, 2025, 04:44 PM
17 hrs ago

although the lower lumbar and S areas are what give me the most pain. I also have fibromyalgia, and my inflammation levels often kick me into lupus flares. I'm in KS, where smiling is looked upon as "what have you done you shouldn't have done?!" I swear, "Illegal Smile" was written about this place! But gods, how I'd love to try what you've found. I've run over to MO for some stuff, which is legal there, but what I found helped for a few weeks but like most meds, my body adapted and it didn't do as well over the long haul. I've been stuck doing pain pills (hydrocodone) for so long, for any kind of relief. But you know how tolerance to those build up. Add to that I worry they're going to end up taking them off the market or make them harder to get as the purists and christianists get wound up even more. Is what you've found offered online, or only through a physical store? I'd pushed the edges for a few day of almost normal behavior of cleaning house again... not to mention sitting on the floor and playing with my cats!

Attilatheblond

(7,342 posts)
9. In AZ, a lot of Cannabis products are legal at licensed dispensaries. There is a steep tax on the stuff
Mon Sep 29, 2025, 05:53 PM
16 hrs ago

Feel for you, especially being in KS. Originally from MO myself, with family still in KS, I TOTALLY get the issues!

So sorry to hear about what you are dealing with. All I can offer is to work to elect better legislators who understand that pain is not required. Or, get thee to MO for a buy. I realize the trip might be impossible, depending on what part of KS you are in. It's a pretty good sized state.

The brand is Wana and there are several products with different formulas. Maybe someone you trust travels east from time to time and could bring you some? Would you be in legal danger just having it in the house in KS?

Years ago, I worked with a woman from China, born to a French father/Chinese mother. Highly educated, very
cosmopolitan and worldly. She worked for the French Ambassador in Peking after the war, married an American officer. A year prior to meeting him, she was engaged to a GI from Kansas. Knowing I am from western MO with family in KS, she asked me what her life would have been like if she had married the man from KS. I was honest and told her it would have been SHORT because she would likely have thrown herself down a well after two years. Then I detailed what her life would have been like.

She listened, wide eyed. When I was done telling her about life there back in the 40s and on, she said, "I need to make my husband a very special dinner to thank him for saving me from that!"

I TRULY hope you find some way to get reliable relief. Yes, I know about the problem of meds losing effectiveness over time. That is why I have to be nearly suicidal before giving in and taking something. The pain and lack of sleep over the years has taken a toll on my mental abilities along with the physical limitations. Yes, I understand and wish you solid help.

edited to change 'sophisticated' to the more accurate 'cosmopolitan'

slightlv

(6,625 posts)
13. My sis and I have taken trips to DT KC in the past,
Mon Sep 29, 2025, 11:34 PM
11 hrs ago

but this summer went by too fast, I guess... that, and money was low. Dispensary prices here are pretty high, too. Still... I was so blown away walking into a "legal" head shop the first time I nearly dropped my teeth! (LOL) The medicated cream I found was great until it ran out, and then the dispensary ran out, and I could never find it again. A substitute didn't work at all.

All I can say about KS and moving back here to help out family decades ago is it got me out of Texas before it became equal to FL. I long to move to a blue PNW state, but age and lack of money isn't going to allow that, I'm afraid. Thanks for the understanding, Attila... I think if we could get out of the constant state of PTSD with the magas and trump, it might help a bit by decreasing the stress. But I don't see that happening anytime soon, either.

Tree Lady

(12,765 posts)
11. My husband has arthritis in the spine
Mon Sep 29, 2025, 06:34 PM
16 hrs ago

And neck. A lot of pain. He just started getting specialized shots in his neck called Medial Branch Blocks and if it works for the pain they will do a Radiofrequency Neurotomy where they put heat on the nerves to deaden them that cause the pain.

He went to a special pain doctor to hear about this.

He smokes pot to help but hates pain pills so doesn't use them often.

So far the first shots they gave him have been working. He said he can move his neck around without pain for first time in years.

Attilatheblond

(7,342 posts)
14. Pain specialist tested the Medial Branch Block on me
Mon Sep 29, 2025, 11:38 PM
11 hrs ago

Glad it helped your husband. Didn't help me at all. We just have to experiment to see what helps, I reckon.

twodogsbarking

(16,004 posts)
7. Gee, who would have thought.
Mon Sep 29, 2025, 05:10 PM
17 hrs ago

Ancient societies in China, India, Egypt, Greece, and Rome used marijuana for thousands of years to treat various types of pain. The specific applications included anesthesia, anti-inflammatory remedies, and relief for conditions like rheumatism and gout

Response to Omaha Steve (Original post)

Response to Bernardo de La Paz (Reply #17)

Bernardo de La Paz

(58,951 posts)
20. I see you do your own research!
Tue Sep 30, 2025, 07:57 AM
2 hrs ago

You must be a genius to know that so much science is wrong when it conflicts with your beliefs. How handy.

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