Testosterone replacement therapy: Is it safe? - ABC News

As social media fills with influencers touting testosterone therapy, experts warn it’s not for everyone and urge patients to consider the potential risks.

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The video discusses the rising popularity of testosterone replacement therapy (TRT), with prescriptions increasing 50% over the last five years. While some patients report dramatic benefits like increased energy, weight loss, and muscle growth, medical experts emphasize important cautions: TRT is only FDA-approved for men with clinically low testosterone levels and specific symptoms, not for anti-aging or performance enhancement.

Key warnings include:

- One size doesn't fit all—requires qualified medical supervision
- Potential side effects: acne, sleep apnea, high blood pressure, infertility (men), excess hair growth and voice deepening (women)
- Can reduce the body's natural testosterone production
- No FDA-approved use for women
- Growing concerns about online clinics overprescribing without proper oversight

The video features success stories from patients who combined TRT with diet and exercise, losing significant weight and improving their well-being. However, experts stress that testosterone won't benefit people with normal levels and carries real risks without proper medical monitoring. An FDA panel recently voted to ease some restrictions, potentially making TRT more accessible, but the need for regular evaluation and qualified physician oversight remains critical.