Galpagos Tomatoes Quietly Reversing Evolution

On the younger, black-rock islands of the Galápagos archipelago, wild-growing tomatoes are doing something peculiar. They're shedding millions of years of evolution, reverting to a more primitive genetic state that resurrects ancient chemical defenses. These tomatoes, which descended from South American ancestors likely brought over by birds, have quietly started making a toxic molecular cocktail that hasn't been seen in millions of years, one that resembles compounds found in eggplant, not the modern tomato.

In a study published recently in Nature Communications, scientists at the University of California, Riverside, describe this unexpected development as a possible case of "reverse evolution," a term that tends to be controversial amongst evolutionary biologists. That's because evolution isn't supposed to have a rewind button. It's generally viewed as a one-way march toward adaptation, not a circular path back to traits once lost. While organisms sometimes re-acquire features similar to those of their ancestors, doing so through the exact same genetic pathways is rare and difficult to prove.

However, reversal is what these tomato plants appear to be doing. "It's not something we usually expect," said Adam Jozwiak, a molecular biochemist at UC Riverside and lead author of the study. "But here it is, happening in real time, on a volcanic island." The key players in this chemical reversal are alkaloids. Tomatoes, potatoes, eggplants, and other nightshades all make these bitter molecules that act like built-in pesticides, deterring insect predators, fungi, and grazing animals. While the Galápagos are famous as a place where animals have few predators, the same is not necessarily true for plants. Thus, the need to produce the alkaloids.

The researchers began this project because alkaloids in crops can be problematic. In high concentrations they are toxic to humans, hence the desire to understand their production and reduce them in the edible parts of fruits and tubers. "Our group has been working hard to characterize the steps involved in alkaloid synthesis, so that we can try and control it," Jozwiak said. What makes these Galápagos tomatoes interesting isn't just that they make alkaloids, but that they're making the wrong ones, or at least, ones that haven't been seen in tomatoes since their early evolutionary days.

Read more: https://www.miragenews.com/galapagos-tomatoes-quietly-reversing-evolution-1483775/