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mahatmakanejeeves

(68,350 posts)
Thu Jan 15, 2026, 05:31 AM 7 hrs ago

"Just astonishing good news. We are on the way to end Multiple Sclerosis. University research delivers."

Reposted by Mike Masnick
https://bsky.app/profile/mmasnick.bsky.social

Michael Clemens
‪@mclem.org‬

Just astonishing good news. We are on the way to end Multiple Sclerosis.

University research delivers. Always has. Now a cabal in the White House is shattering it.

‪Dr. Keith R. Brunt‬
‪@profbrunt.bsky.social‬
· 8h
Epstein-Barr Virus #EBV was linked to #MultipleSclerosis - now a plausible cause has been found, misidentification by longterm memory T-cells that pick on the wrong protein, ANO2, instead of the EBV-antigen. Massive inflection towards the elimination of MS!!!
🧪🧠Cell
https://www.cell.com/cell/fulltext/S0092-8674%2825%2901481-3

Anoctamin-2-specific T cells link Epstein-Barr virus to multiple sclerosis
Researchers identified anoctamin-2 (ANO2) as a frequent autoimmune target in multiple
sclerosis, with T cell responses against ANO2 occurring in over half of patients.
These ANO2-specific T cells shar...
www.cell.com
9:33 PM · Jan 14, 2026

Just astonishing good news. We are on the way to end Multiple Sclerosis.

University research delivers. Always has. Now a cabal in the White House is shattering it.

Michael Clemens (@mclem.org) 2026-01-15T02:33:22.289Z


Dr. Keith R. Brunt
‪@profbrunt.bsky.social‬

Epstein-Barr Virus #EBV was linked to #MultipleSclerosis - now a plausible cause has been found, misidentification by longterm memory T-cells that pick on the wrong protein, ANO2, instead of the EBV-antigen. Massive inflection towards the elimination of MS!!!
🧪🧠Cell
https://www.cell.com/cell/fulltext/S0092-8674%2825%2901481-3

Anoctamin-2-specific T cells link Epstein-Barr virus to multiple sclerosis
Researchers identified anoctamin-2 (ANO2) as a frequent autoimmune target in multiple
sclerosis, with T cell responses against ANO2 occurring in over half of patients.
These ANO2-specific T cells shar...
www.cell.com
8:41 PM · Jan 14, 2026

Epstein-Barr Virus #EBV was linked to #MultipleSclerosis - now a plausible cause has been found, misidentification by longterm memory T-cells that pick on the wrong protein, ANO2, instead of the EBV-antigen. Massive inflection towards the elimination of MS!!!
🧪🧠Cell www.cell.com/cell/fulltex...

Dr. Keith R. Brunt (@profbrunt.bsky.social) 2026-01-15T01:41:46.305Z
5 replies = new reply since forum marked as read
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"Just astonishing good news. We are on the way to end Multiple Sclerosis. University research delivers." (Original Post) mahatmakanejeeves 7 hrs ago OP
This is awesome! FakeNoose 5 hrs ago #1
RFK jr tamping this down in 5, 4, 3, 2.... flying rabbit 4 hrs ago #2
While I understand the importance of University research, "breakthrough" announcements of this type... NNadir 1 hr ago #3
"Hope is a good thing, maybe the best of things." lastlib 1 hr ago #4
That may be true in movies, but false hope can be, and often is, NNadir 1 hr ago #5

FakeNoose

(40,297 posts)
1. This is awesome!
Thu Jan 15, 2026, 07:22 AM
5 hrs ago


Most of these research studies have been funded by the federal government in one way or another. What's happening to these programs now, with their funds disappearing, is criminal....

NNadir

(37,337 posts)
3. While I understand the importance of University research, "breakthrough" announcements of this type...
Thu Jan 15, 2026, 12:03 PM
1 hr ago

...are to my mind highly problematic since they often generate false hope.

I recall from many years ago, when the New York Times announced, on the front page, Judah Folkman's discovery of the role of angiogenesis in cancer, a hypothesis he validated by using interferon alpha to block angiogenesis in mouse tumors. He was besieged with calls for access to the protein which was at the time (1980) not accessible via gene modifications. Exasperated, he told a reporter that he could cure cancer in a few mice, but would be unable to produce the protein for humans. (Ultimately anti-angiogensis drugs were developed, notably Avastin, one of the early antibody drugs. It came to market more than 20 years after Folkman's discovery.)

The relationship between anoctamin-2, epstein-barr and the autoimmune cascade response leading to MS has been known for some time, and was reported in 2016 in PNAS (Ayoglu, 2016).

We need to be sober about these reports which can and do generate false hopes.

lastlib

(27,602 posts)
4. "Hope is a good thing, maybe the best of things."
Thu Jan 15, 2026, 12:09 PM
1 hr ago

--Andy Dufresne, The Shawshank Redemption

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