General Discussion

Disease List
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List of mitochondrial diseases
AI Overview
What is Mitochondrial Dysfunction? - Tempo Bioscience
Mitochondrial diseases are a group of disorders caused by dysfunctional mitochondria, leading to a wide array of symptoms that can affect multiple body systems, particularly the brain, muscles, and heart. Common types include MELAS (Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes), MERRF (Myoclonic Epilepsy with Ragged Red Fibers), NARP (Neuropathy, Ataxia, and Retinitis Pigmentosa), Kearns-Sayre syndrome, and Leigh syndrome. Symptoms can vary greatly depending on the specific genetic mutation and the tissues affected.

Also:
Leber Hereditary Optic Neuropathy (LHON):
LHON primarily affects the optic nerve, causing vision loss.
It is typically inherited maternally, meaning it's passed down through the mother's mitochondrial DNA (mtDNA).
Various mtDNA mutations can cause LHON.