Obese Children Twice As Likely To Develop Multiple Sclerosis; Chronic Inflamm, Risk Other Diseases: Study [View all]

- 'Obese children twice as likely to develop multiple sclerosis, study suggests,' The Guardian, March 28, 2024. - Swedish researchers say inflammation caused by obesity is likely to increase risk of developing conditions such as MS. -Edit.

Children who are obese may face more than double the risk of developing multiple sclerosis as adults, a study suggests. MS can affect the brain and spinal cord, causing a range of potential symptoms including problems with vision, arm or leg movement, sensation or balance. It is a lifelong condition that can sometimes cause serious disability. The findings are from the Karolinska Institute in Stockholm, Sweden.

The research team looked at data on children aged two to 19 who joined the registry between 1995 and 2020, and compared their information with that of children in the general population. The study included data on more than 21,600 children with obesity, who started treatment for obesity when they were an average age of 11, and more than 100,000 children without obesity.

Children involved in the study were tracked for an average of six years. During the follow-up period, MS was diagnosed in 28 of those with obesity (0.13% of the group) and 58 in the group without obesity (0.06%). The average age of MS diagnosis was comparable between groups, with patients diagnosed on average when they were 23. Despite the limited follow-up time, our findings highlight that obesity in childhood increases the susceptibility of early-onset MS more than twofold.”

The study’s authors said: “One of the effects of obesity in childhood is that it causes a low-grade but chronic inflammation, and most probably this inflammation increases the risk to develop several diseases such as MS. “It is also believed that chronic low-grade inflammation increases the risk for other such diseases as asthma, arthritis, type 1 diabetes, and some forms of cancers. However, we know that weight loss reduces the inflammation and most likely the risk to develop such diseases.”...
https://www.theguardian.com/society/2024/mar/28/obese-children-multiple-sclerosis-study