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2. The findings
Sun Jun 8, 2025, 11:27 AM
Jun 8

Mayo Clinic laboratories analyzed two types of proteins in blood plasma associated with the accumulation of amyloid plaques, a central feature of Alzheimer's disease: Aβ42/40 and p-tau217. The researchers observed that p-tau217 levels were higher in patients with Alzheimer's compared to those without the disease. In addition, they found that higher concentrations of p-tau217 in plasma were also associated with impaired kidney function, a factor that, according to the researchers, should be taken into account when performing blood tests.

Plasma p-tau217 concentrations were positive in 267 of the 509 patients, including 233 of the 246 patients (95%) with cognitive impairment attributed to Alzheimer's disease.

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Note that the study did not concentrate on amyloid which was never found to be the cause

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