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Happy Hoosier

(9,008 posts)
3. I'm not a biochemist, so I can't tell...
Tue Nov 30, 2021, 12:05 PM
Nov 2021

... but my main concern would be the other metabolic effects of using a treatment like this.

A major problem with using insulin in T2D patients is that it's a bit of a downward spiral without some fairly dramatic dietary changes. Insulin isn't just the hormone that regulates glucose uptake, it is involved in a number of metabolic processes including fat storage. It's difficult for a T2D patient to lose weight while using insulin injections because the use of insulin tends to exacerbate insulin resistance, requiring more and more use over time, and that leads to all kinds of complications from hyperinsulinemia.

If the use of this venom can encourage glucose uptake without the other metabolic effects of insulin, it could very well be an effective treatment for insulin resistance, especially when aired with dietary changes. The key is treating the insulin resistance, however, and NOT just lowering blood glucose levels. I mean, keeping blood glucose in the safe region is important, but it's more of a dangerous symptom than a cause.

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