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ShazzieB

(20,803 posts)
Mon Feb 10, 2025, 07:01 AM Feb 2025

Several Psychiatric Disorders Share The Same Root Cause, Study Reveals [View all]

https://www.sciencealert.com/several-psychiatric-disorders-share-the-same-root-cause-study-reveals

Researchers recently discovered that eight different psychiatric conditions share a common genetic basis. A new study has now honed in on some of those shared genetic variants to understand their properties. They found many are active for longer during brain development and potentially impact multiple stages, suggesting they could be new targets to treat multiple conditions.

"The proteins produced by these genes are also highly connected to other proteins," explains University of North Carolina geneticist Hyejung Won. "Changes to these proteins in particular could ripple through the network, potentially causing widespread effects on the brain."

In 2019 an international team of researchers identified 109 genes that were associated in different combinations with eight different psychiatric disorders, including autism, ADHD, schizophrenia, bipolar disorder, major depressive disorder, Tourette syndrome, obsessive-compulsive disorder, and anorexia.

This may explain why so many of these conditions present with similar symptoms or turn up together, like the link between autism and ADHD. Up to 70 percent of people who have one have the other too, and they often both show up in the same families.


Tho article is blowing my mind. There are all kinds of mental illnesses and neurodivergency in my family, incliding schizophrenia, a variety of mood disorders, and ADHD. Knowing that each of these conditions can run in families, I always thought it was weird that my family tree has so many different ones. Finally, someone seems to be connecting those dots, and I feel so seen!
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